The Spine Institute at RMSO in partnership with The Premier Stem Cell Institute has the most extensive research and data regarding all realms of regenerative medicine. We have developed and compiled data for years. Our team of fellowship trained Doctors have treated thousands of patients with various stem cell procedures.
A stem cell procedure harnesses and amplifies the body's natural mechanism for healing (and anti-inflammation). This mechanism uses adult autologous stem cells (Mesenchymal stem cells) derived from your own bone marrow. Autologous stem cells (Mesenchymal stem cells) have been shown to be anti-inflammatory which helps in healing, and they also have antimicrobial properties. Mesenchymal stem cells (MSCs), have immune regulatory properties which may stop the immune system from attacking the myelin sheath.
Every individual is different. Two key determinants for success are dependent on the severity of your condition and your body’s response to stem cell therapy. At The Premier Stem Cell Institute, we provide consultations with patients from around the world to determine whether their candidacy for stem cell therapy and/or platelet-rich plasma.
In the procedure, the physician will aspirate bone marrow from the iliac crest of your pelvis, concentrate it, then deliver it back into your body intravenously. In all, the process takes less than 45 minutes.
Because your procedure will utilize a concentrated preparation of your own cells, the procedure is considered "autologous point-of-care". The procedure is fast, and in most cases can be completed with moderate sedation.
Stem cell procedures are usually done as an outpatient, meaning there is no need for an overnight hospital stay. With an intravenous stem cell procedure, most patients should expect to walk out of the clinic and resume low-impact activities immediately.
The most important part of any stem cell therapy is adhering to your post-procedure restrictions that will be covered before your procedure. For the procedure to have the best chance to yield lasting benefit, our physicians strongly recommend:
When people age, particularly women, they often lose height and weight and develop a stooped posture. A bone-thinning disease called osteoporosis often causes these body changes. Osteoporosis causes the destruction of bone tissue, which leads to loss of bone mass. As a result, bones become brittle and the risk of fracture of the spine, hip, and wrist increases. Spinal fractures are the most common type of fractures due to osteoporosis. Forty percent of all women will have at least one spinal fracture by the time they are 80 years old. These vertebral fractures can permanently alter the shape and strength of the spine.
Most women are likely to feel some effects of osteoporosis in their lifetime, but the good news is that much can be done to reduce and even prevent loss of bone mass and fractures. New treatments for osteoporosis are being discovered each year. You can also actively work to decrease your chances of suffering the effects of osteoporosis. The key is prevention and intervention.
Loss of bone mass begins at around age 30. Although men can be affected by osteoporosis, older women are usually affected, particularly those who are past menopause. Bone loss becomes worse in women after menopause because of the body’s lack of estrogen. When bones lose mass, they tend to weaken and become fragile. This increases the risk of fracture under stress or because of a fall, particularly in the spine and hip.
Falls in elderly women are often actually the result, rather than the cause, of hip fractures. In other words, a fragile hip bone may simply fracture, causing the person to fall. In severe cases of osteoporosis, the bones can fracture with any kind of slight movement, leaving some people bedridden.
Doctors have identified two types of osteoporosis, primary and secondary. Primary osteoporosis is further divided into “primary type I” and “primary type II” osteoporosis.
Most people think of this type when talking about osteoporosis. It is the form that mainly affects women after menopause. Primary Type I osteoporosis is six times more common in women than men and typically occurs in women 15 to 20 years after menopause. The loss of bone is linked to an estrogen deficiency in women and a testosterone deficiency in men. Amounts of these hormones tend to become low with age.
Primary Type I osteoporosis is sometimes called high-turnover osteoporosis because it causes a rapid loss of the spongy inner part of the bones (called trabecular bone). Normally there is a large amount of trabecular bone in the vertebral bodies of the spine and in the end of the long bones, like the wrist. People who lose trabecular bone have a higher risk of spine and wrist fractures.
Compared to Type I, Type II osteoporosis is only two times more common in women than men. It typically occurs when people reach their 70s or 80s. It is also thought to be the result of too little calcium in the diet, low Vitamin D levels because of age, or increased activity of the parathyroid glands.
Primary Type II osteoporosis causes a loss of both hard outer bone and spongy inner bone. Because the rate of bone turnover is much lower, Primary Type II osteoporosis is also called low-turnover osteoporosis. Hip fractures are the most common result of this type of osteoporosis.
In healthy people, bone is constantly regenerating. New bone is formed while old bone is resorbed by the body. This process is called remodeling. The amount of bone mass you have depends on the balance between bone formation and bone resorption. This is your bone turnover rate. If bone production is less than the amount of bone being resorbed, the risk of developing osteoporosis increases. In secondary osteoporosis, the rate of bone remodeling increases, leading to a loss of bone mass. Secondary osteoporosis can also occur from an imbalance in hormones due to the following diseases:
Secondary osteoporosis can also occur from disorders where the bone marrow cavity expands at the expense of the trabecular or spongy bone, which causes bones to lose some of their strength.
Other causes of secondary osteoporosis include:
The most common symptoms of osteoporosis are fractures, particularly vertebral compression fractures and hip fractures. Compression fractures in the spine are caused by weakened vertebrae and can lead to pain in the mid-back. These fractures often stabilize by themselves and the pain eventually goes away. But the pain may persist if the crushed bone continues to move around and break.
In severe cases of osteoporosis, actions as simple as bending forward can be enough to cause a crush fracture in a vertebra. This type of vertebral fracture causes loss of body height and a humped back, especially in elderly women. This disorder, called kyphosis, is an exaggeration in the curve of the mid-back. It causes the shoulders to slump forward and the top of the back to look enlarged and humped.
Consult your doctor if you have symptoms of osteoporosis. Older women should discuss their risks with their doctor, even if they are not currently showing any signs of osteoporosis. All women should be aware of the many preventive steps that can lower their risk of developing osteoporosis.
Osteoporosis does not affect everyone. There are risk factors that may predict your chances of developing it. Some risk factors are genetic, meaning you inherited them from your biological parents. Some risks are due to medical conditions that you may not be able to avoid, such as use of particular medications. Risk factors that are considered to be lifestyle-related are the ones that you can change.
Whether you are at risk or not, below are some things you can do to help keep your bones healthy and prevent osteoporosis.
Increasing your calcium intake is the easiest thing you can do to help prevent osteoporosis. You can increase your calcium intake by eating foods that are high in calcium or by taking a calcium supplement. It is best for people to begin adequate calcium intake at an early age, as bone mass begins to decrease around the age of 30. After age 30, calcium helps decrease bone loss, strengthen bones, and decrease the risk of fractures.
The recommended daily intake of calcium for women 25 to 50 years old and women over 50 who take hormone replacements is 1,000 mg per day. Women over 50 who do not take hormone replacements should take 1,500 mg of calcium per day. Men 25 to 65 years old should take 1,500 mg of calcium per day. Men and women over age 65 should take 1,500 mg of calcium per day.
If you take calcium supplements, make sure they contain Vitamin D, as this helps with absorption. Also, look for calcium citrate because it is absorbed better than calcium carbonate. If you take the carbonate form, make sure you take it with food.
To help prevent bone loss and fracture, adults should take at least 800 mg per day of vitamin D. Many calcium supplements contain vitamin D. You can also get vitamin D through foods such as egg yolks, fish, and fortified milk and cereals. Halibut, mackerel, sardines, shrimp, pink salmon, and cod liver oil are good sources of vitamin D.
Exercising five days a week for at least 30 minutes helps reduce the risk of bone loss. The best exercises for maintaining bone mass are weight-bearing exercises like walking, low-impact aerobics, and safe forms of dancing. Always check with your doctor before starting an exercise program.
Currently there are four medications that are approved by the US Food and Drug Administration (FDA) to help prevent bone loss and osteoporosis.